bone cements, bone regeneration, polyethylene glycol, brushite phase
Brushite bone cement containing polyethylene glycol for bone regeneration. Bio-Medical Materials and Engineering, 33(3), 221-233This study aimed to investigate the effect of using polyethylene glycol (PEG) on brushite bone cement to obtain desirable handling times and to evaluate its regeneration in vivo. PEG 4000 was synthesized with wollastonite by phosphorization reaction to form brushite, which was further cured by oven drying. The addition of PEG exhibited handling times of 60 min with a low increase in temperature during curing. Brushite phase of ~71% was obtained after cement hardening, with good compressive strength (25 MPa) and decent values of … The in vivo experiments were conducted using rabbits as a tibial bone defect model. The results suggest that the addition of PEG to brushite bone cement may significantly modify its properties, making it a promising candidate for bone regeneration applications.